The administration of GLP-1RA exendin-4 restored microglial homeostasis, reduced cytokine secretion, and limited astrocyte activation, especially of the A1 phenotype, as well as reduced neuronal apoptosis
This is what happened when there was a shortage of commercial GLP-1s shortly after they first became available for treating obesity
According to the prescribing information, the most common side effects are injection site reactionsincluding skin rash, itchy skin, and hivesafter administering the dose of Ajovy from the prefilled syringe
This is needed to detoxify and protect cells from damage
Hoeijmakers JG, Faber CG, Lauria G, Merkies IS, Waxman SG
Presented for research literature review only Yan H et al